产品货号:
Z13400
中文名称:
CHCHD6抗体
英文名称:
Anti-CHCHD6 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CHCHD6 Antibody |
指标别名 | CHCHD6;CHCM1;MIC25 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB |
基因名称 | CHCHD6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6.The immunogen is located within amino acids 20 - 70 of CHCHD6. |
计算分子量 | 26kDa |
成分 | CHCHD6 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CHCHD6 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin,SAM50,metaxins 1 and 2,and CHCHD3.CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth,ATP production and oxygen consumption.This decrease of CHCHD6 also led to a reduction in mitofilin protein levels,while a knockdown of mitofilin resulted in a reduced level of CHCHD6,suggesting coordinate regulation between these two proteins.CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs,suggesting that CHCHD6 may be a potential therapeutic anti-tumor target. |
Uniprot ID | Q9BRQ6 |
基因名全称 | Coiled-coil-helix-coiled-coil-helix domain containing 6 |
蛋白名全称 | Coiled-coil-helix-coiled-coil-helix domain containing 6 |
推荐稀释比 | CHCHD6 antibody can be used for detection of CHCHD6 by Western blot at 1 ~ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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